Non-coding RNAs in viral myocarditis.

Author: Jie HU ¹ ; Yangyang ZHU ¹ ; Qiong YUAN ¹ ; Dan YAN ¹ ; Chaozhi LI ¹ ; Hengzhong GUO ¹ ; Lili LU ¹
Author Information

1. Institute of Pharmaceutical Innovation, College of Medicine, Wuhan University of Science and Technology, Wuhan 430065, Hubei, China.
Publication Type:Review
Keywords: coxsackievirus; non-coding RNAs; pathogenesis; therapeutic target; viral myocarditis
MeSH: Coxsackievirus Infections; Enterovirus B, Human; Humans; Inflammation; Myocarditis/genetics*; Virus Diseases/genetics*
From: Chinese Journal of Biotechnology 2021;37(9):3101-3107
CountryChina
Language:Chinese
Abstract: Viral myocarditis (VMC) is a disease characterized by inflammation of myocardial cells caused by viral infection. Since the pathogenesis mechanism of VMC has not been fully elucidated, the diagnosis and treatment of this disease remains extremely challenging. Non-coding RNAs (ncRNAs) are a class of RNAs that do not encode proteins. An increasing number of studies have shown that ncRNAs are involved in regulating the occurrence and development of VMC, thus providing potential new targets for the treatment and diagnosis of VMC. This review summarizes the possible roles of ncRNAs in the pathogenesis and diagnosis of VMC revealed recently.