Deletion of CD36 gene ameliorates glucose metabolism abnormality induced by high-fat diet and promotes liver lipid accumulation.
- Author:
Xiao-Qing LUO
1
;
Han ZENG
1
;
Wei TAN
1
;
Ping YANG
1
;
Ya-Xi CHEN
1
;
Xiong-Zhong RUAN
2
Author Information
1. Chongqing Key Laboratory of Lipid and Glucose Metabolism, Centre for Lipid Research, Chongqing Medical University, Chongqing 400016, China.
2. Chongqing Key Laboratory of Lipid and Glucose Metabolism, Centre for Lipid Research, Chongqing Medical University, Chongqing 400016, China. xiongzruan@foxmail.com.
- Publication Type:Journal Article
- MeSH:
Animals;
Diet, High-Fat/adverse effects*;
Fatty Liver/metabolism*;
Glucose/metabolism*;
Insulin/metabolism*;
Insulin Resistance;
Lipid Metabolism;
Liver;
Mice;
Triglycerides
- From:
Acta Physiologica Sinica
2021;73(5):805-812
- CountryChina
- Language:Chinese
-
Abstract:
This study aimed to investigate the effects and the underlying mechanism of CD36 gene on glucose and lipid metabolism disorder induced by high-fat diet in mice. Wild type (WT) mice and systemic CD36 knockout (CD36
