Slit-Lamp Examination of the Experimentally Induced HSV-I Keratitis.
- Author:
Dong Cheol KIM
1
;
Myung Kyoo KO
Author Information
1. Department of Ophthalmology, School of Medicine, Hanyang University, Seoul, Korea.
- Publication Type:Original Article
- MeSH:
Cornea;
Keratitis*;
Keratitis, Herpetic;
Wounds and Injuries
- From:Journal of the Korean Ophthalmological Society
1988;29(2):251-255
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
This study was performed to observe the sequential charge of the morpholcgic characteristics in experimentally induced herpes simplex keratitis. Duration and morphology of corneal lesion following infection of rabbit cornea with the Kos strain of HSV-I were followed by a daily slit-lamp examination. Three types of virus inoculation methods were used such as scratching, deepithelialization, and intrastromal injection. Herpetic corneal lesions appeared 24 hours after inoculation with punctate and dendritic figures. They persisted up to 14 or 15 days. The characteristic finding in punctate herpetic keratitis was grouped, round-shaped, punctate lesion. When scratching method was emplyed, the most remarkable finding was the discontinuity of the lesion occurred along the scratching wound at relatively regular intervals. There was no difference in lesional morphology and duration between three inoculation methods.
