The Standardization of Visual Evoked Potential in Pigmented Rabbits.
- Author:
Jae Yong BAE
1
;
Si Yeol KIM
Author Information
1. Department of Ophthalmology, Kyungpook National University, Taegu, Korea.
- Publication Type:Original Article
- MeSH:
Electrodes;
Evoked Potentials, Visual*;
Optic Nerve Diseases;
Rabbits*
- From:Journal of the Korean Ophthalmological Society
1988;29(2):309-314
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
VEP is an objective method for the evaluation of macular function and optic nerve disease, but its large inter and intraindividual variation prevented clinical and experimental application. We recorded a relatively stable VEP A wave in pigmented rabbits with cortical electrode and following results were obtained. The amplitude of VEP A wave was 97.8 +/- 29.8 micro V and latent time was 52.2 +/- 6.9 msec. Inter- and intraindividual variation of VEP latent time was much smaller than that of VEP amplitude. So latent time of VEP A wave may be a good indicator in evaluation of pharmacologic and toxicologic experiment of systemically administered drug.
