Diarrhea-predominant irritable bowel syndrome of spleen deficiency and damp excess treated with fire needling therapy with filiform needle and acupoint application therapy: a randomized controlled trial.
10.13703/j.0255-2930.20200904-k0001
- Author:
Hao SHI
1
,
2
;
Yue NIU
3
;
Qian HUANG
4
;
Zheng-Ming YANG
4
;
Li YANG
4
Author Information
1. Department of Acupuncture-Moxibustion, 3Department of Gastroenterology, Lianyungang Hospital of TCM Affiliated to Kangda College of Nanjing Medical University, Lianyungang 222000, Jiangsu Province, China
2. Clinical Medicine Department of Kangda College of Nanjing Medical University, Lianyungang 222000, Jiangsu Province.
3. Department of Gastroenterology, Lianyungang Hospital of TCM Affiliated to Kangda College of Nanjing Medical University, Lianyungang 222000, Jiangsu Province, China.
4. Department of Acupuncture-Moxibustion, Lianyungang Hospital of TCM Affiliated to Kangda College of Nanjing Medical University, Lianyungang 222000, Jiangsu Province, China.
- Publication Type:Randomized Controlled Trial
- Keywords:
acupoint application;
diarrhea-predominant irritable bowel syndrome, spleen deficiency and damp excess;
fire needling therapy with filiform needle;
randomized controlled trial (RCT)
- MeSH:
Acupuncture Points;
Acupuncture Therapy;
Diarrhea/therapy*;
Humans;
Irritable Bowel Syndrome/therapy*;
Quality of Life;
Spleen;
Treatment Outcome
- From:
Chinese Acupuncture & Moxibustion
2021;41(9):984-990
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To compare the clinical therapeutic effect on diarrhea-predominant irritable bowel syndrome (IBS-D) of spleen deficiency and damp excess among fire needling therapy with filiform needle combined with acupoint application therapy, simple acupoint application therapy and pinaverium bromide tablets, and explore the mechanism on the improvements in IBS-D.
METHODS:A total of 150 patients with IBS-D of spleen deficiency and damp excess were randomized into a combined treatment group (50 cases, 14 cases dropped off), an acupoint application group (50 cases, 16 cases dropped off ) and a western medication group (50 cases, 13 cases dropped off ). In the western medication group, pinaverium bromide tablets were prescribed for oral administration, 50 mg per time, three times a day. In the acupoint application group, the herbal plaster of
RESULTS:Except the score for abdominal pain in the acupoint application group and the scores for abdominal pain and abdominal distention in the western medication group after 7 days of treatment, the scores for abdominal pain, abdominal distention, defecation frequency, stool form and incomplete bowel movement after 7 and 28 days of treatment were all reduced as compared with those before treatment in each group separately (
CONCLUSION:The combined treatment with the fire needling therapy with filiform needle and the acupoint application therapy effectively relieves the clinical symptoms, improves the quality of life and strengthens the immunity in the patients with IBS-D. The therapeutic effect of this combined regimen is better than either simple acupoint application therapy or the oral medication of pinaverium bromide. The mechanism may be related to the regulation of the levels of T lymphocyte subsets and the modulation of the expressions of 5-HT3R and 5-HT4R mRNA in colon tissue.
