Extracellular Matrix of the Cultured Retinal Pigment Epithelial Cells.
- Author:
Myung Kyoo KO
1
;
Joon Kiu CHOE
Author Information
1. Department of Ophthalmology, School of Medicine, Hanyang University, Seoul, Korea.
- Publication Type:In Vitro ; Original Article
- MeSH:
Collagen Type IV;
Epithelial Cells*;
Extracellular Matrix*;
Fibronectins;
Membranes;
Retinaldehyde*
- From:Journal of the Korean Ophthalmological Society
1988;29(2):331-335
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
This study was undertaken in an attempt to localize fibronectin and collagen type IV to the cultured retinal pigment epithelial cell by means of immunofluorescent staining and immunocytochemrcal method. Immunofluorescent staining and immunocytochemical methcds revealed fibronectin and collagen type IV localized on the extracellular membrane of the cultured retinal pigment epithelial cell. Ultrastructural immunocytochemical technique also revealed fibronectin associated with extracellular tissue. This study demonstrated that fibronectin and collagen type IV are an integral component of the extracellular matrix of the retinal pigment epithelial cell in vitro.
