Prevention and therapeutic strategies and targeted immunotherapy for hepatocellular carcinoma recurrence and metastasis after liver transplantation
10.3969/j.issn.1674-7445.2022.02.018
- VernacularTitle:肝癌肝移植术后复发转移的防治策略和靶向免疫治疗
- Author:
Xiaoyan QIN
1
;
Yanyao LIU
;
Quan KANG
Author Information
1. Department of General Surgery and Trauma Surgery of Yuzhong District, Children's Hospital of Chongqing Medical University, Key Laboratory of Child Development and Disorders of Ministry of Education, National Clinical Research Center for Child Health and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing 400014, China
- Publication Type:Research Article
- Keywords:
Liver transplantation;
Hepatocellular carcinoma;
Recurrence;
Metastasis;
Immunosuppressant;
Radiofrequency ablation;
Transcatheter arterial chemoembolization;
Targeted therapy
- From:
Organ Transplantation
2022;13(2):271-
- CountryChina
- Language:Chinese
-
Abstract:
With the development and maturity of liver transplant techniques, liver transplantation has become one of the vital treatment options for hepatocellular carcinoma (HCC). Postoperative recurrence and metastasis of HCC after liver transplantation is one of critical factors that affect the long-term survival of recipients. Exploring the prevention and therapeutic strategies for HCC recurrence and metastasis after liver transplantation plays a pivotal role in improving the clinical efficacy of liver transplantation for HCC recipients. Intimate monitoring, active prevention, early diagnosis, comprehensive surgical treatment and local treatment, especially targeted immunotherapy, and individualized prevention and therapeutic strategies are of significance for the prevention and treatment of HCC recurrence and metastasis after liver transplantation. In this article, the monitoring, diagnosis, prevention and treatment of tumor recurrence and metastasis after liver transplantation for HCC were reviewed, aiming to provide reference for the prevention and treatment of tumor recurrence and metastasis after liver transplantation, enhancing clinical efficacy of liver transplantation and prolonging the survival of recipients.
