Hemodynamic Study on the Relationship Between Collateral Circulation Caused by Iliac Vein Compression and Deep Venous Thrombosis
10.16156/j.1004-7220.2022.01.16
- VernacularTitle:髂静脉狭窄导致侧支循环与下肢深静脉血栓关联的血流动力学研究
- Author:
Xudong JIANG
1
;
Tianze XU
1
;
Lili SUN
1
;
Xiaoqiang LI
2
;
Peng WU
3
Author Information
1. Department of Vascular Surgery, the Second Affiliated Hospital of Soochow University
2. Department of Vascular Surgery, the Second Affiliated Hospital of Soochow University；Department of Vascular Surgery, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School
3. rtificial Organ Technology Laboratory, School of Mechanical and Electric Engineering, Soochow University
- Publication Type:Journal Article
- Keywords:
deep venous thrombosis (DVT);
iliac vein compression syndrome (IVCS);
collateral circulation;
computational fluid dynamics (CFD)
- From:
Journal of Medical Biomechanics
2022;37(1):E105-E111
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between the establishment of collateral circulation caused by iliac vein compression syndrom(IVCS) and the deep venous thrombosis (DVT). Methods Different types of ideal collateral circulation models and IVCS patient-specific models were numerically simulated using computational fluid dynamics (CFD) in combination with the blood stasis model. The relationship between blood retention and collateral types and cross-sectional area was studied, and the relationship with thrombosis was explored. Results Wall shear stress (WSS) at the distal end part of each ideal model was 0.3 Pa. After four cardiac cycles, the residual blood stayed at the stenosis and the distal end part for the lumbar ascending and pelvic type models, the old blood volume fraction (OBVF) varied with collateral cross-sectional areas, ranging from 5%-90% and 70%-80%, respectively. The OBVF of the coexistence model was above 80%. The WSS at the distal end part of the patient-specific model was 0.9 Pa, and the OBVF at the distal end part was 51.5%. Conclusions The stenosis and the distal end part are most prone to blood stasis, and closely related with DVT. The larger the collateral cross-sectional area, the more serious the blood stagnation. Blood stagnation of the coexistence model is higher compared with the model with lumbar ascending type and pelvic type.
