Interaction between obesity/central obesity and hypertension
10.19485/j.cnki.issn2096-5087.2022.02.005
- Author:
Liangliang WANG
;
Yu HUANG
;
Wei GUO
;
Xingmin WEI
;
Ning FAN
;
Guixue ZHAO
;
Yahui XIE
;
Dongjing MA
;
Yunchao WANG
;
Xinhua WANG
;
Jianjun WU
- Publication Type:Journal Article
- Keywords:
hypertension;
obesity;
central obesity;
interaction
- From:
Journal of Preventive Medicine
2022;34(2):129-134
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To examine the effects of obesity and central obesity on hypertension, so as to provide insights into the prevention and control measures of hypertension.
Methods:From September to December 2018, residents at ages of 35 to 75 years were sampled using the multi-stage random sampling method in Baiyin District, Baiyin City, Gansu Province, and subjected to questionnaire surveys and physical examinations. The interaction between obesity/central obesity and hypertension was evaluated using logistic regression analysis. The synergy index ( SI ), relative excess risk due to interaction ( RERI ) and attributable proportion due to interaction ( AP ) were calculated using Excel compiled by Andersson et al.
Results:A total of 6 246 questionnaires were allocated and 6 169 valid questionnaires were recovered, with an effective recovery rate of 98.77%. The respondents included 3 038 men ( 49.25% ) and 3 131 women (50.75%), with a mean age of ( 52.05±8.78 ) years. There were 832 respondents with obesity ( 13.49% ) and 2 278 with central obesity ( 36.93% ). The crude and standardized prevalence rates of hypertension were 35.89% and 33.05%, respectively. Multivariable logistic regression analysis showed that obesity ( OR=2.020, 95%CI: 1.705-2.393 ) and central obesity ( OR=1.622, 95%CI: 1.433-1.836 ) were statistically associated with hypertension. There was no multiplicative interaction between obesity or central obesity and hypertension ( OR=1.011, 95%CI: 0.655-1.560 ), and no additive interaction was detected between obesity or central obesityand hypertension ( SI=1.405, 95%CI: 0.815-2.424; RERI=0.658, 95%CI: -0.298 to 1.614; AP=0.201, 95%CI: -0.075 to 0.476 ).
Conclusions:Obesity and central obesity increase the risk of hypertension; however, no interaction is detected between obesity or central obesity and hypertension.
- Full text:肥胖和中心性肥胖对高血压的交互作用分析 (1).pdf
