Research progress of pharmacological effects and clinical application of Trollius chinensis
- VernacularTitle:金莲花药理作用及临床应用研究进展
- Author:
Ping SUN
1
;
Xinpeng LI
1
;
Tao XUE
1
;
Jie XIN
1
;
Yuchao CHEN
2
;
Shenghu GUO
2
;
Bo ZHANG
1
Author Information
1. College of Pharmacy，Linyi University，Shandong Linyi 276005，China
2. Agricultural Biotechnology Center，Ningxia Academy of Ag riculture and Forestry Science，Yinchuan 750002，China
- Publication Type:Journal Article
- Keywords:
Trollius chinensis;
pharmacological effects;
clinical application
- From:
China Pharmacy
2022;33(4):507-512
- CountryChina
- Language:Chinese
-
Abstract:
Trollius chinensis has a wide range of pharmacological effects ，including anti-oxidative ，antibacterial，antiviral， anti-inflammatory，anti-tumor，anti-aging，antipyretic and analgesic effects ，relieving cough and removing phlegm ，viscera protection，and so on. Flavonoids and phenolic acids are the main medicinal components of it ，especially three monomers have a wide range of efficacy and have been studied more ，such as orientin ，vitexin and 2″-O-galactopyranosyl orientin. T. chinensis is mostly used in clinical practice in the form of Chinese patent medicines ，such as Jinlianhua granules ，Jinlianhua capsules ， Jinlianhua tablets and Jinlianhua oral liquid. These medicines are used to treatment of upper respiratory tract infection ，pharyngitis， tonsillitis，periodontitis，mumps，oral ulcer ，and hand-foot-mouth disease. They are usually used by combining with Western medicine. Due to its definite curative effect and less adverse drug reactions ，T. chinensis related preparations are more suitable for pediatric population ，and they can be used for the treatment of upper respiratory tract infection in children ，acute suppurative tonsillitis in children ，epidemic mumps in children ，hand-foot-mouth disease in children ，which is also one of its drug characteristics. This paper review the relevant literatures in recent 20 years from the respective of pharmacological effects and clinical applicationin order to provide reference for further promoting rational clinical application of T. chinensis and new drug research and development.
