METHODS: Retrospective study. A total of 126 patients(126 eyes)with primary pterygium treated in the ophthalmology department of our hospital during 2018-01/2019-09 were selected as subjects. According to the mode of operation, the patients were divided into observation group(64 eyes, 64 cases in seamless autologous conjunctival transplantation group)and control group(62 eyes, 62 cases in suture group). The operation time, postoperative wound healing time, ocular irritation symptoms, tear film rupture time and postoperative recurrence were compared between the two groups.

RESULTS: The operation time of the patients in the observation group was significantly shorter than that in the control group(t=6.19, P<0.01); The conjunctival healing time in the observation group was significantly shorter than that in the control group(t=12.82, P<0.01). The incidence of irritation symptoms in the control group was significantly lower than that in the control group(χ2=6.46, P=0.01). Except that there was no difference in the comparison of tear film rupture between the two groups before operation(t= -0.033, P>0.05), the comparison at different time points and the comparison between the two groups after operation were statistically significant(all P<0.05).There was no recurrence at 6 and 12mo in the observation group, but 1 eye and 2 eyes in the control group at 6 and 12mo, respectively. There was no significant difference in postoperative recurrence rate between the two groups(P >0.05).

CONCLUSION: Pterygium excision combined with seamless autologous conjunctival transplantation has a definite effect on pterygium, reduces the incidence of postoperative irritation symptoms, shortens the operation time and helps to promote postoperative conjunctival healing.