Association of short-term exposure to ambient air pollution with hospital admission for ischemic stroke among older adults
10.3969/j.issn.1006-2483.2022.01.002
- VernacularTitle:大气污染物短期暴露对老年人缺血性脑卒中住院的影响研究
- Author:
Ruijun XYU
1
;
Yunshao YE
2
;
Qiaoxuan LIN
2
;
Lan ZHANG
3
;
Qi TIAN
2
;
Yuewei LIU
1
Author Information
1. School of Public Health, Sun Yat-sen University, Guangzhou 510080, China
2. Guangzhou Health Technology Identification & Human Resources Assessment Center, Guangzhou 510080, China
3. Institute of Chronic Disease Control, Hubei Center for Disease Control and Prevention , Wuhan 430079 , China
- Publication Type:Journal Article
- Keywords:
Air pollution;
Ischemic stroke;
Hospital admission
- From:
Journal of Public Health and Preventive Medicine
2022;33(1):6-11
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the association between short-term exposure to ambient air pollution and hospital admission for ischemic stroke among older adults. Methods Using clinical monitoring data from China National Health Commission, we identified 124 297 individuals from Guangzhou, Guangdong province, China who were 60 years or older and were admitted to hospital for ischemic stroke in 2016-2019. We used a time-stratified case-crossover design and employed the conditional logistic regression model to investigate the exposure-response association between short-term exposure to air pollution and hospital admission for ischemic stroke. Based on each subject's residential address and pollutant data from its neighboring air quality monitoring stations, we used an inverse distance weighting method to assess individual-level exposure to PM2.5, PM10, SO2, NO2, CO and O3 on each of the case and control days. Results In single-pollutant models, each 10 µg/m3 increase of PM2.5, PM10, SO2, NO2, CO and O3 was associated with a 0.46% (95% confidence interval [CI]: 0.13-1.36%, lag 2 d), 0.66% (1.38-2.93%, lag 02 d), 3.39% (0.07-0.21%, lag 2 d), 1.47% (0.07-0.21%, lag 02 d), 0.06% (0.07-0.21%, lag 02 d) and 0.18% (0.07-0.21%, lag 3 d) increase in odds of hospital admission, respectively. The results of 2-pollutant models showed that the association of exposure to SO2, NO2 and O3 with hospital admission for ischemic stroke remained stable with adjustment for each of the other air pollutants. Conclusions Short-term exposure to ambient air pollution, especially SO2, NO2 and O3, was associated with increased risk of hospital admission for ischemic stroke in older adults.
