Mucosa-Associated Lymphoid Tissue Lymphoma Arising from the Ethmoid Sinus Mucosa: A Case Report and Review of the Literature
10.3342/kjorl-hns.2019.00227
- Author:
Young Woo LEE
1
;
Young Min MOON
;
Seok Joo LEE
;
Hyung-Ju CHO
Author Information
1. Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Korea
- Publication Type:Case Report
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2020;63(7):319-323
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Most of nasal cavity or paranasal sinuses lymphoma reported in Korea is either diffuse large Bcell lymphoma or natural killer/T-cell lymphoma. There are only three cases of mucosa-associated lymphoid tissue lymphoma (MALTOMA), which has so far been reported only in a Korea journal and all of which have occurred in the nasal cavity and in the turbinate. We experienced a case of MALTOMA of ethmoid sinus extending to the orbital cavity. It was confirmed by the findings of immunohistochemical staining (positive with CD20, Bcl-2, and Granzyme B, negative with CD5, CD56, Bcl-6 and Cyclin D1). The patient underwent radiation therapy and the lesion was successfully resolved without recurrence for 16 months.