Streptococcus Mutans Biofilm Inhibition Effect of Indocyanine Green and Near Infrared Diode Laser
10.5933/JKAPD.2020.47.4.446
- Author:
Yeowon KIM
1
;
Howon PARK
;
Juhyun LEE
;
Hyunwoo SEO
;
Siyoung LEE
Author Information
1. Department of Pediatric Dentistry, Oral Science Research Center, College of Dentistry, Gangneung-Wonju National University
- Publication Type:1
- From:
Journal of Korean Academy of Pediatric Dentistry
2020;47(4):446-453
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The purpose of this study was to evaluate the effect of Indocyanine Green (ICG) and near-infrared (NIR) diode laser on Streptococcus mutans biofilms depending on ICG concentrations.
S. mutans biofilms were formed on a Hydroxyapatite disk, and 0.5, 1.0, 2.0, 3.0, 4.0, 5.0 mg/mL ICG solutions dissolved in sterile distilled water and a NIR diode laser having a power of 300 mW and a wavelength of 808 nm were applied to the biofilms. The temperature changes of the biofilm surface according to the concentrations of the ICG solution were measured using a 1-channel thermocouple thermometer.
Compared to the control group, in the groups with only the 3.0, 4.0, 5.0 mg/mL ICG solution application, and in the groups with the 1.0, 2.0, 3.0, 4.0, 5.0 mg/mL ICG solution application and light irradiation, a statistically significant decrease in the bacterial counts were observed.
The temperature increase according to the concentration of the ICG solutions was 9.53℃, 10.43℃, 11.40℃, 12.10℃, 12.67℃, and 13.63℃ in ICG solutions of 0.5, 1.0, 2.0, 3.0, 4.0, and 5.0 mg/mL respectively.This study presents the potential for clinical application of ICG and NIR diode lasers as a new method for preventing dental caries.
