Micro-computed tomographic evaluation of the effect of fluoride agents on white spot lesions:An in vitro study
10.4041/kjod.2022.52.1.75
- Author:
Sook-Chan HONG
1
;
Dong-Yul LEE
;
Yae-Jin KIM
Author Information
1. Major in Dentistry, Department of Medicine, Graduate School of Korea University, Seoul, Korea
- Publication Type:Brief Report
- From:The Korean Journal of Orthodontics
2022;52(1):75-79
- CountryRepublic of Korea
- Language:English
-
Abstract:
Objective:To investigate remineralizing effect of three fluoride regimens on artificially demineralized enamel around orthodontic bracket by analyzing mineral density (MD) acquired from micro-computed tomography (micro-CT).
Methods:Forty-eight bracket bonded bovine incisors were prepared to create demineralized enamel (DE) surface. The samples were divided into four groups according to the fluoride regimen: 1) no fluoridation, 2) 1.23% acidulated phosphate fluoride (APF) gel, 3) fluoridated toothpaste, and 4) 0.05% sodium fluoride mouthwash. Micro-CT was scanned after demineralization (T0), and 2 weeks (T1) and 4 weeks (T2) of fluoridation.
Results:APF gel showed highest remineralization of DE during T1–T0 interval among the groups (p < 0.05); followed by toothpaste, mouthwash and no fluoridation. APF gel and toothpaste demonstrated significant increase in MD after 4 weeks of application (p < 0.05).
Conclusions:Remineralization effects of three fluoride regimens were depicted through micro-CT analysis, of which APF gel was most effective.
