Prognostic significance of malnutrition for long-term mortality in community-acquired pneumonia: a propensity score matched analysis
- Author:
Hye Ju YEO
1
;
Ki Sup BYUN
;
Junhee HAN
;
June Hyun KIM
;
Seung Eun LEE
;
Seong Hoon YOON
;
Doosoo JEON
;
Yun Seong KIM
;
Woo Hyun CHO
Author Information
- Publication Type:Original Article
- From:The Korean Journal of Internal Medicine 2019;34(4):841-849
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND/AIMS:The impact of malnutrition on the outcome of hospitalized adults with community-acquired pneumonia (CAP) has not been fully investigated. This study evaluated the prevalence and prognostic significance of malnutrition in a Korean population with CAP.
METHODS:In total, 198 patients with CAP from November 2014 to September 2015 were analyzed retrospectively. We assessed the prevalence of malnutrition and the risk factors for 2-year mortality. Furthermore, we divided the patients into two groups: elderly (age ≥ 65 years, n = 131) and non-elderly (age < 65 years, n = 67). Subgroup analyses were performed in the elderly group through propensity score matching.
RESULTS:The prevalence of malnutrition was 39.4%, and the proportion of patients with malnutrition was significantly higher (53.4% vs. 11.9%, p < 0.001) in the elderly group than in the non-elderly group. In-hospital mortality, 1-year mortality, and 2-year mortality rates were 4.5%, 19.2%, and 26.8%, respectively. Multivariate Cox regression analyses revealed that malnutrition (odds ratio [OR], 2.52; 95% confidence interval [CI], 1.39 to 4.60; p = 0.002) and the Charlson comorbidity index score (OR, 1.30; 95% CI, 1.17 to 1.45; p < 0.001) were associated with 2-year mortality.
CONCLUSIONS:Malnutrition was common and associated with a poor long-term outcome in patients with CAP, particularly the elderly. A routine nutritional assessment at admission is mandatory as a first step for appropriate nutritional therapy.
