The role of lipids in the pathophysiology of coronavirus infections
10.24171/j.phrp.2021.0153
- Author:
Milad ZANDI
1
;
Parastoo HOSSEINI
;
Saber SOLTANI
;
Azadeh RASOOLI
;
Mona MOGHADAMI
;
Sepideh NASIMZADEH
;
Farzane BEHNEZHAD
Author Information
1. Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
- Publication Type:Review Article
- From:
Osong Public Health and Research Perspectives
2021;12(5):278-285
- CountryRepublic of Korea
- Language:English
-
Abstract:
Coronaviruses, which have been known to cause diseases in animals since the 1930s, utilize cellular components during their replication cycle. Lipids play important roles in viral infection, as coronaviruses target cellular lipids and lipid metabolism to modify their host cells to become an optimal environment for viral replication. Therefore, lipids can be considered as potential targets for the development of antiviral agents. This review provides an overview of the roles of cellular lipids in different stages of the life cycle of coronaviruses.