Simultaneous Determination of Four Compounds from Cercidiphyllum japonicum Using HPLC-UV Analysis
- Author:
Jeongyeon KANG
1
;
Hyeon Seok JANG
;
Ju Yeol KIM
;
Min Sung LEE
;
Young Soo BAE
;
Yongsoo KWON
;
Heejung YANG
Author Information
- Publication Type:Original Article
- From:Natural Product Sciences 2021;27(4):280-283
- CountryRepublic of Korea
- Language:English
- Abstract: Cercidiphyllum japonicum is being used for the treatment of obesity and liver fibrosis in Korean local clinics. In the present study, we tried to develop an analytical methodology for the determination of the chemical markers of Cercidiphyllum japonicum. Four chemicals, maltol (1), chlorogenic acid (2), quercetin (3), and avicularin (4), were selected for method validation, and the analytical conditions were optimized and validated using high-performance liquid chromatography coupled with an ultraviolet detector (HPLC-UV). Additionally, the seasonal variations of four markers were monitored every month for six months. The contents of four chemicals markers were most detected in a sample collected in June.
