A clear cell hepatocellular carcinoma in an obese dog with hyperlipidemia: a case report
10.14405/kjvr.2021.61.e34
- Author:
Jae-Ha JUNG
1
;
MaRo LEE
;
Yeseul YANG
;
Dansong SEO
;
Sung-Hyun HWANG
;
Wan Hee KIM
;
Yongbaek KIM
Author Information
1. Laboratory of Clinical Pathology, College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea
- Publication Type:Case Report
- From:Korean Journal of Veterinary Research
2021;61(4):e34-
- CountryRepublic of Korea
- Language:English
-
Abstract:
An 11-year-old obese dog was referred for a liver mass. Cytologic examination revealed vacuolated hepatocytes with mild pleomorphism. A partial liver lobectomy was performed. On histopathologic examination, the mass was diagnosed as hepatocellular carcinoma composed of hepatocytes with clear vacuoles. These findings were consistent with clear cell hepatocellular carcinoma (CCHCC). The CCHCC is a rare subtype of hepatocellular carcinoma in dogs, and clinical features are poorly defined. This is the first report on the cytological, histological and clinical aspects of CCHCC, suggesting that obesity and hyperlipidemia are potential risk factors for CCHCC in dogs.
