Prevalence and molecular characterization of novel recombinant enterovirus G isolates in Jeju Province of South Korea
10.14405/kjvr.2019.59.2.89
- Author:
Ji Hyun JEON
1
;
Changhee LEE
Author Information
1. Animal Virology Laboratory, School of Life Sciences, BK21 Plus KNU Creative BioResearch Group, Kyungpook National University, Daegu 41566, Korea. changhee@knu.ac.kr
- Publication Type:Original Article
- From:Korean Journal of Veterinary Research
2019;59(2):89-96
- CountryRepublic of Korea
- Language:English
-
Abstract:
Enterovirus species G (EV-G) is highly diverse, and is ubiquitous in pig populations, usually without diarrhea. The present study aimed to investigate the presence of novel EV-G recombinants with the torovirus papain-like cysteine protease (PLCP) in Jeju pig herds. EV-G1-PLCP mono-infections were most prevalent in diarrheic weaned piglets. The PLCP genes of the Jeju isolates varied in size and junction sequences, and were greatly heterogeneous, with 77.0–90.7% homology amongst all recombinants. Our results suggest that the exogenous PLCP gene has undergone continuous rapid mutation in the individual EV-G genomes following cross-order recombination, thereby causing clinical disease in swine.
