Peptic Ulcer Disease Associated with Helicobacter pylori Infection.
10.4166/kjg.2016.67.6.289
- Author:
Se Hwan YEO
1
;
Chang Hun YANG
Author Information
1. Division of Gastroenterology & Hepatology, Department of Internal Medicine, Dongguk University School of Medicine, Gyeongju, Korea. chhyang@dongguk.ac.kr
- Publication Type:Review
- Keywords:
Helicobacter pylori;
Peptic ulcer;
Prevalence;
Epidemiology;
Therapy
- MeSH:
Epidemiology;
Gastrointestinal Diseases;
Helicobacter pylori*;
Helicobacter*;
Korea;
Peptic Ulcer*;
Prevalence;
Virulence Factors
- From:The Korean Journal of Gastroenterology
2016;67(6):289-299
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Although the global prevalence of peptic ulcer disease (PUD) is decreasing, PUD is still one of the most common upper gastrointestinal diseases in the world due to Helicobacter pylori infection and increased use of non-steroidal anti-inflammatory drugs. In Korea, the prevalence of H. pylori infection is also declining, but it is still the major cause of PUD. The outcomes of H. pylori infection are caused by imbalances between bacterial virulence factors, host factors, and environmental influences. In this review, we describe the prevalence trends of H. pylori infection in Korea, the mechanism of H. pylori infection-related PUD, and treatment strategies.
