MRI Criteria for Predicting Invasive Lesions in Biopsy-Proven Ductal Carcinoma in Situ
10.3348/jksr.2019.80.6.1203
- Author:
Jiyeong LEE
1
;
Ko Woon PARK
;
Eun Young KO
;
Boo Kyung HAN
;
Eun Sook KO
;
Ji Soo CHOI
;
Meeyoung NAM
;
Soo Youn CHO
Author Information
1. Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. claudel@skku.edu
- Publication Type:Original Article
- From:Journal of the Korean Radiological Society
2019;80(6):1203-1213
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE:To evaluate the criteria for predicting invasive lesions with preoperative breast MRI in ductal carcinoma in situ (DCIS) histopathologically diagnosed with biopsy.
MATERIALS AND METHODS:We retrospectively analyzed the preoperative MRI findings of 80 percutaneous biopsy-proven DCIS. The morphological type, enhancement distribution and kinetics, and extent of the lesions were analyzed. We compared the results of pure DCIS and DCIS with invasive lesions. We evaluated the MRI criteria for predicting DCIS with invasive lesions and assessed its diagnostic performance.
RESULTS:Of the 80 DCIS lesions analyzed, 27 contained co-existing invasive lesions and 49 were pure DCIS. No residual lesions after biopsy were seen in 4 cases. DCIS with invasive lesions showed washout kinetics more frequently and to a larger extent than did pure DCIS (p = 0.030 and p = 0.048, respectively). Using enhancement kinetics and the lesion cut-off value of 4 cm yielded the highest diagnostic performance, with 92.6% sensitivity and 93.8% negative predictive value for predicting invasive lesions.
CONCLUSION:Washout kinetics and the lesion extent of at least 4 cm are useful criteria for the prediction of co-existing invasive lesions in patients with DCIS diagnosed with biopsy.
