Small Breast Cancer (≤ 5 mm): Ultrasonographic Features and Clinical and Pathological Characteristics
10.3348/jksr.2019.80.4.728
- Author:
Hye Young KWON
1
;
Eun Suk CHA
;
Jee Eun LEE
;
Jeoung Hyun KIM
;
Jin CHUNG
Author Information
1. Department of Radiology, Ewha Womans University Mokdong Hospital, Seoul, Korea. aqua0724@ewha.ac.kr
- Publication Type:Original Article
- From:Journal of the Korean Radiological Society
2019;80(4):728-739
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE:To identify differences in ultrasonography (US) feature, clinical and pathological characteristics including immunohistochemical characteristics between small breast cancer (pathologic size ≤ 5 mm) and large breast cancer (> 5 mm).
MATERIALS AND METHODS:A total of 528 invasive breast cancer lesions in 475 patients were included. US features with clinical and pathological characteristics were evaluated according to pathologic size. US Breast Imaging-Reporting and Data System findings and final assessments were recorded for each lesion. Standard references were based on surgical pathologies.
RESULTS:Of 528 invasive breast cancer lesions, 62 were small breast cancers. Small breast cancers showed a higher rate of oval, round shape, parallel orientation; circumscribed margin; and iso/solid and cystic echo pattern, with no posterior feature. The final assessment of category 4 was also a dominant factor in small breast cancer. Early stage, asymptomatic state, and extensive ductal carcinoma in situ component were associated with small breast cancers.
CONCLUSION:Our results show that small breast cancers have less suspicious US features than large breast cancers.