Comparison of CT Findings of Non-Tuberculous Mycobacterial Pulmonary Infection: Disease Stable versus Progressed Group
10.3348/jksr.2018.79.2.57
- Author:
Go Eun YANG
1
;
Heon HAN
;
Ji Young HONG
;
Taek Geun OHK
Author Information
1. Department of Radiology, Kangwon National University Hospital, Chuncheon, Korea. hanheon@kangwon.ac.kr
- Publication Type:Original Article
- From:Journal of the Korean Radiological Society
2018;79(2):57-62
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE:To compare initial CT findings of non-tuberculous mycobacteria (NTM) pulmonary infection between stable and progressed groups and determine whether they could be used to predict disease prognosis and treatment response.
MATERIALS AND METHODS:From July 2006 to October 2013, 71 patients with NTM infection were retrospectively reviewed. Lung lesion pattern of CT finding, specific species, disease duration, and follow-up period were analyzed. These patients were classified into NTM stable (n = 46) and progressed (n = 25) groups.
RESULTS:The most common CT findings of NTM infection were small nodules (n = 71, 100%) and bronchiectasis (n = 67, 94%). Large consolidation (> 2 cm, n = 34, 48%) and involvement of more than four lobes (n = 49, 69%) were also commonly observed. According to disease prognosis, large consolidation (n = 18, 72%, p = 0.003), cavitary lesion (n = 17, p = 0.002), and involvement of four or more lobes (n = 21, p = 0.044) on CT were significantly more frequent in disease progressed group than that in the stable group.
CONCLUSION:Among common CT findings of NTM disease, some CT findings such as large consolidation, cavitary lesion, and disease extent are good predictors of response to treatment in NTM pulmonary disease.
