Micronutrients and superoxide dismutase in postmenopausal women with chronic periodontitis: a pilot interventional study.
10.5051/jpis.2014.44.4.207
- Author:
Sunita DAIYA
1
;
Rajinder Kumar SHARMA
;
Shikha TEWARI
;
Satish Chander NARULA
;
Paramjeet KUMAR SEHGAL
Author Information
1. Department of Periodontics and Oral Implantology, Post Graduate Institute of Dental Sciences, Rohtak, India. rksharmamds@yahoo.in
- Publication Type:Clinical Trial ; Original Article
- Keywords:
Antioxidants;
Clinical trial;
Chronic periodontitis;
Root planning
- MeSH:
Antioxidants;
Chronic Periodontitis*;
Debridement;
Female;
Hemorrhage;
Humans;
Inflammation;
Micronutrients*;
Root Planing;
Superoxide Dismutase*
- From:Journal of Periodontal & Implant Science
2014;44(4):207-213
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: The study was aimed at investigating changes in periodontal parameters and superoxide dismutase activity triggered by root surface debridement with and without micronutrient supplementation in postmenopausal women. METHODS: Forty-three postmenopausal chronic periodontitis patients were divided into two groups: group 1 (n=22) were provided periodontal treatment in the form of scaling and root planing (SRP) and group 2 (n=21) patients received SRP along with systemic administration of micronutrient antioxidants. Patients in both groups were subjected to root surface debridement. Group 2 patients also received adjunctive micronutrient antioxidant supplementation. Serum and salivary superoxide dismutase (SOD) activity along with periodontal parameters were recorded at baseline and 3 months after therapy. RESULTS: Salivary and serum SOD values significantly (P<0.05) improved with periodontal treatment. Improvement in systemic enzymatic antioxidant status along with reduction in gingival inflammation and bleeding on probing (%) sites was significantly greater in group 2 as compared to group 1. CONCLUSIONS: Adjunctive micronutrient supplements reduce periodontal inflammation and improve the status of systemic enzymatic antioxidants in postmenopausal women.
