Comparisons of Neuropsychological Characteristics of Elderly Subjects With Versus Without History of Agent Orange Exposure
10.4306/jknpa.2021.60.4.346
- Author:
Seunggyu HAN
1
;
Jinhee CHOI
;
Hyung Seok SO
;
Hayun CHOI
;
Hong Jin JEON
;
Jinseob KIM
;
Kiwon KIM
Author Information
1. Department of Psychiatry, Veteran Health Service Medical Center, Seoul, Korea
- Publication Type:ORIGINAL ARTICLE
- From:Journal of Korean Neuropsychiatric Association
2021;60(4):346-353
- CountryRepublic of Korea
- Language:English
-
Abstract:
Objectives:Agent Orange is a defoliant chemical that is widely known for its use by the U.S. military during the Vietnam War. It is known to be associated with the occurrence of various diseases in exposed subjects. However, few previous studies have focused on the effects of exposure to Agent Orange on cognitive dysfunction.
Methods:A total of 387 male subjects participated in the study. They were divided into those who were exposed to Agent Orange (n=301) and those without exposure (n=86). Both were evaluated with neuropsychological batteries, including the Consortium to Establish a Registry for Alzheimer’s Disease and the Seoul Neuropsychological Screening Battery-Second Edition.
Results:The group exposed to Agent Orange showed significantly higher scores in the Rey Complex Figure Test copy and recognition compared to those without exposure.
Conclusion:In this study, we compared the effects of exposure to Agent Orange on cognitive function in groups that had not yet progressed to dementia. The Agent Orange exposure group showed better results in some tests evaluating visuospatial and memory function.
