Serum Uric Acid Levels In Korean Adult Population And Their Correlates.
- Author:
Bin YOO
1
Author Information
1. Devision of Clinical Immunology, Asan Medical Center, College of Medicine, Ulsan University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Uric acid;
Hyperuricemia;
Epidemiology;
Risk factor
- MeSH:
Adult*;
Calcium;
Creatinine;
Epidemiology;
Female;
Humans;
Hypertension;
Hyperuricemia;
Logistic Models;
Male;
Mass Screening;
Multiple Endocrine Neoplasia Type 1;
Obesity;
Odds Ratio;
Prevalence;
Risk Factors;
Urate Oxidase;
Uric Acid*
- From:The Journal of the Korean Rheumatism Association
1995;2(1):60-68
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: To investigate the distribution of serum uric acid levels among 20000 Korean people who visited health screening center and relationships between serum uric acid and a number of biological variables. METHODS: By descriptive analysis on obesity index, blood pressures and various chemical measurements. Serum uric acid levels were measured by uricase method. Stepwise regression analysis of serum uric acid levels on various host variables selected on the basis of univariate analysis was perfomed. Logistic regression analysis was performed for the odds ratios for hyperuricemia. RESULTS: The mean serum uric acid level and prevalence of hyperuricemia were 5.9+/-1.3 mg/dl, 16.6% respectively in men and 4.2+/-l.0mg/dl, 1.69% in women. Serum creatinine concentration was by far the most important correlate with serum uric acid level. Obesity index, serum calcium, triglycerid were also significantly associated with serum uric acid in both sexes. Contributing factors for hyperuricema were calcium, serum GPT and obesity index in both sexes, and serum trig]yceride level, age, hypertension in men only. CONCLUSIONS: The mean serum uric acid level in men is higher than in women throughout all ages and the uric acid level arised after 5th decade in women. There are differences in contributing factors for serum uric acid level between sexes as well as in risk factor for hyperuricemia.
