A Case Of Dermatomyositis Associated With Uterine Cervical Cancer.
- Author:
Kwae Soo KYUNG
1
;
Young Soo SONG
;
Jung Su KIM
;
Seong Hun HAN
;
Hye Kyung LEE
;
Yun Woo LEE
Author Information
1. Department of Internal medicine, Seoul Paik Hospital, College of Medicine, Inje University, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Dermatomyositis;
Uterine cervical cancer
- MeSH:
Aged;
Atrophy;
Biopsy;
Breast;
Carcinoma, Squamous Cell;
Connective Tissue;
Deglutition Disorders;
Dermatomyositis*;
Elbow;
Exanthema;
Female;
Hand;
Head;
Humans;
Inflammation;
Knee;
Lung;
Metrorrhagia;
Muscle Weakness;
Muscle, Skeletal;
Myositis;
Pneumonia, Aspiration;
Prednisolone;
Quadriceps Muscle;
Skin;
Stomach;
Uterine Cervical Neoplasms*;
Wrist
- From:The Journal of the Korean Rheumatism Association
1995;2(1):82-86
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Dermatomyositis is a group of connective tissue disorders characterized by non-suppurative inflammation of the skeletal muscle and skin lesions. It is associated with malignancy, especially of the stomach, lung, overy and breast. we report a case of dermatomyositis with uterine cervical concer. A 78 year old female patient was admitted because of progressive proximal muscle weakness, skin rashes, and vaginal spotting. She was bedridden because of severe proximal muscle weakness and atrophy, unable to elevate her head, and suffered from dysphagia. Gottron's patches were found on the knuckles of the hands, scaly erythematous rashes on the extensor surfaces of bilateral elbows, wrists and knees. The serum concentrations of muscle enzymes were elevated, the biopsy of quadriceps muscle showed the features comparable with myositis, and the uterine cervical biopsy revealed squamous cell carcinoma, which was determined to be in stage lib by pelvic CT. Radiotherapy(total 3240 cGy) was done for the cervical cancer and prednisolone (initially 60mg/day) was given for the dermatomyositis. The muscle power improved only a little although the concentrations of serum muscle enzmes returned to normal. She deceased of aspiration pneumonia 43 days after the admission.
