A Case Of Primary Biliary Cirrhosis Anteceded By Rheumatoid Arthritis.
- Author:
Pyoung Nam KIM
1
;
Tae Hwan KIM
;
Seong Yoon KIM
;
Jae Bum JUN
;
Dong See HAN
;
Sung See JUNG
;
In Hong LEE
;
Sang Cheol BAE
;
Dae Hyun YOO
;
Kyung Bin JOE
;
Seung Young KIM
Author Information
1. Rheumatism Center, Department of Internal Medicine, College of Medicine, Hanyang University, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Rheumatoid arthritis;
Primary biliary cirrhosis
- MeSH:
Alkaline Phosphatase;
Arthralgia;
Arthritis, Rheumatoid*;
Bile Ducts;
Cholestasis, Intrahepatic;
Congenital Abnormalities;
Female;
Fibrosis;
Humans;
Joints;
Liver;
Liver Cirrhosis, Biliary*;
Liver Diseases;
Middle Aged
- From:The Journal of the Korean Rheumatism Association
1995;2(1):92-97
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Primary biliary cirrhosis is a chronic, progressive liver disease characterized by inflammatory destruction of septal and intralobular bile ducts which results in intrahepatic cholestasis. Although the cause remains obscure, it is frequently associated with a variety of disorders presumed to be autoimmune in nature. We report a case of early primary biliary cirrhosis which was anteceded by rheumatoid arthritis. The patient was a 54-year-old female who was admitted due to arthralgia and joint deformity. She had been diagnosed as having rheumatoid arthritis 10 years before. On admission, she had elevated serum ALT, AST, alkaline phosphatase, gamma-GTP and positive serum antimitochondrial antibody test. Microscopic findings of the liver were consistent with the early stage of primary bi]iary cirrhosis.
