Nosocomial Outbreak Caused by NDM-5 and OXA-181 Carbapenemase Co-producing Escherichia coli
- Author:
Kwangjin AHN
1
;
Gyu Yel HWANG
;
Young Keun KIM
;
Hyo Youl KIM
;
Hye Ran JEONG
;
Jun Sung HONG
;
Young UH
Author Information
- Publication Type:Brief Communication
- From:Infection and Chemotherapy 2019;51(2):177-182
- CountryRepublic of Korea
- Language:English
- Abstract: Carbapenemase-producing Enterobacteriaceae (CPE) is an important and increasing threat to global health. From July to September 2017, 20 inpatients at a tertiary care hospital in Korea were either colonized or infected with carbapenem-resistant Escherichia coli strains. All of E. coli isolates co-produced bla(NDM-5) and bla(OXA-181) carbapenemase genes and shared ≥88% clonal relatedness on the basis of a cladistic calculation of the distribution of pulsed-field gel electrophoresis patterns. Rapid detection of CPE is one of the most important factors to prevent CPE dissemination because it takes long time for CPE to become negative.
