Thalamic syndrome and cortical hypoperfusion on technetium-99m HM-PAO brain SPECT.
10.3349/ymj.1989.30.2.151
- Author:
Myung Sik LEE
1
;
Il Saing CHOI
;
Tae Sub CHUNG
Author Information
1. Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Thalamic syndrome;
HM-PAO brain SPECT;
cortical hypoperfusion
- MeSH:
Brain/*radionuclide imaging;
Female;
Human;
Male;
Middle Age;
Organotechnetium Compounds;
Oximes;
Pain/etiology;
Syndrome;
Technetium/diagnostic use;
Technetium Tc 99m Exametazime;
Thalamic Diseases/*radionuclide imaging;
Tomography, Emission-Computed, Single-Photon
- From:Yonsei Medical Journal
1989;30(2):151-157
- CountryRepublic of Korea
- Language:English
-
Abstract:
The six patients included in this study had painful dysesthesia, resulting from vascular lesions in or near the thalamus, confirmed by computerized tomography(CT) brain scan. Using hexamethyl propyleneamine oxime(HM-PAO) single photon emission computed tomography(SPECT) brain scanning, regional cerebral perfusion(rCP) was demonstrated. In contrast to three patients with lesions near the thalamus who showed symmetrical cortical radioactivity, the other three patients with thalamic lesions revealed decreased rCP in the ipsilateral cerebral cortex on HM-PAO brain SPECT. We thought that the loss of afferent activating stimuli from the thalamus led to decreased cortical neuronal activity and the following hypoperfusion. In patients with thalamic syndrome resulting from thalamic lesions, the role of the remote effect of the thalamic damage and consequent cortical deregulation in the development of thalamic pain and/or neuropsychological symptoms cannot be excluded completely.
