Advances in polydopamine-based drug delivery systems for tumor targeting
10.16438/j.0513-4870.2021-1151
- VernacularTitle:基于聚多巴胺特性构建的肿瘤靶向药物递送系统的研究进展
- Author:
Yu-pei SU
1
;
Hao PAN
2
;
Dan-dan LIU
3
,
4
;
Jia-hui WANG
1
;
Ping-tian DING
1
;
Wei-san PAN
1
Author Information
1. School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China
2. School of Pharmacy, Liaoning University, Shenyang 110036, China
3. School of Biomedical &
4. Chemical Engineering, Liaoning Institute of Science and Technology, Benxi 117004, China
- Publication Type:Research Article
- Keywords:
polydopamine;
rug delivery system;
neoplasm;
nanoparticle;
pharmaceutical preparation
- From:
Acta Pharmaceutica Sinica
2022;57(1):25-35
- CountryChina
- Language:Chinese
-
Abstract:
Polydopamine (PDA) is a novel type of polymer synthesized inspired by adhesion proteins in mussels. It has been widely used in tumor-targeting drug delivery systems due to its natural advantages such as good biocompatibility, excellent photothermal conversion performance, adhesion, high chemical reactivity and multiple drug release response mechanisms. This review summarizes the applications of PDA-based tumor-targeting drug delivery in recent years, hoping to provide references for designing a more reasonable and effective PDA-based multifunctional collaborative tumor therapy platform.