Research advances in the protective effect of sulforaphane against liver injury and related mechanisms
10.3969/j.issn.1001-5256.2022.01.036
- VernacularTitle:莱菔硫烷对肝损伤的保护作用及相关机制研究进展
- Author:
Xinyu MA
1
;
Tingting DUAN
1
;
Jingya XU
1
;
Jiahe ZHAO
1
;
Chunlei ZHANG
2
;
Baolong LI
1
Author Information
1. Center for Safety Evaluation of Drugs, Heilongjiang University of Chinese Medicine, Harbin 150040, China
2. Jiamusi College, Heilongjiang University of Chinese Medicine, Jiamusi, Heilongjiang 154000, China
- Publication Type:Reviews
- Keywords:
Sulforaphane;
Liver Injury;
Pathologic Processes
- From:
Journal of Clinical Hepatology
2022;38(1):206-209
- CountryChina
- Language:Chinese
-
Abstract:
Sulforaphane is a phytochemical with a variety of biological activities that exists widely in Cruciferae plants. This article summarizes the recent experimental studies of sulforaphane in the treatment of various types of liver injury in China and globally and reviews the role and mechanism of sulforaphane in protecting against liver injury. Based on the experimental animal models of liver injury, this article summarizes the therapeutic effect of sulforaphane on the models of chemical liver injury, drug-induced liver injury, alcoholic liver injury, immunological liver injury, and ischemia/reperfusion liver injury and analyzes the mechanism of action of sulforaphane in improving experimental liver injury, so as to provide a reference for in-depth research on sulforaphane in protecting against liver injury.
