Research advances in
10.3969/j.issn.1001-5256.2022.01.035
- VernacularTitle:非酒精性脂肪性肝病体外模型的研究进展
- Author:
Xiaochen LU
1
;
Hongmei HAN
1
Author Information
1. Department of Gastroenterology, The Affiliated Hospital of Yanbian University, Yanji, Jilin 133000, China
- Publication Type:Reviews
- Keywords:
Non-alcoholic Fatty Liver Disease;
Models, Theoretical;
Pathologic Processes;
Therapeutics
- From:
Journal of Clinical Hepatology
2022;38(1):201-205
- CountryChina
- Language:Chinese
-
Abstract:
The incidence rate of nonalcoholic fatty liver disease (NAFLD) is increasing year by year, with limited treatment methods, and its pathogenesis is a research hotspot at present. In order to better clarify its pathogenesis, it is urgent to develop advanced, safe, and effective in vitro or in vivo models to understand and develop treatment strategies for this disease. This article reviews the in vitro models commonly used in the preclinical study of NAFLD and discusses their advantages and disadvantages, so as to provide a theoretical basis for the pathogenesis and treatment of NAFLD.
