Research advances in nonalcoholic fatty liver disease-related hepatocellular carcinoma
10.3969/j.issn.1001-5256.2022.01.034
- VernacularTitle:非酒精性脂肪性肝病相关肝细胞癌的研究进展
- Author:
Xuelian GU
1
;
Junfeng LI
2
;
Xiaorong MAO
2
Author Information
1. The First Clinical Medical School of Lanzhou University, Lanzhou 730000, China
2. Department of Infectious Diseases, The First Hospital of Lanzhou University, Lanzhou 730000, China
- Publication Type:Reviews
- Keywords:
Non-alcoholic Fatty Liver Disease;
Carcinoma, Hepatocellular;
Oxidative Stress
- From:
Journal of Clinical Hepatology
2022;38(1):196-200
- CountryChina
- Language:Chinese
-
Abstract:
The incidence rate of nonalcoholic fatty liver disease-related hepatocellular carcinoma (NAFLD-HCC) tends to increase worldwide, while its pathogenesis remains unclear. With reference to the literature in recent years, this article summarizes the role of adipose tissue inflammation, oxidative stress, gut microbiota, and insulin resistance in the pathogenesis of NAFLD-HCC and the advances in the prevention and treatment of the above mechanisms, so as to provide new ideas for the treatment of NAFLD-HCC.
