Research advances in interferon-stimulated genes in treatment of hepatitis B virus infection
10.3969/j.issn.1001-5256.2022.01.031
- VernacularTitle:干扰素刺激基因抗HBV感染的研究进展
- Author:
Yunwen LIAN
1
;
Xingrong ZHENG
1
;
Hewei WU
1
;
Zhiliang GAO
1
;
Xiyao CHEN
1
;
Chan XIE
1
Author Information
1. Department of Infectious Diseases, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China
- Publication Type:Reviews
- Keywords:
Hepatitis B, Chronic;
Interferons;
Interferon Stimulating Gene
- From:
Journal of Clinical Hepatology
2022;38(1):180-186
- CountryChina
- Language:Chinese
-
Abstract:
Hepatitis B virus (HBV) infection is closely associated with the adverse events such as liver cirrhosis, liver cancer, and liver failure and remains a serious threat to human health. Pegylated interferon is an indispensable drug for the treatment of chronic hepatitis B (CHB), and interferon-stimulated genes are associated with a variety of viruses, but few studies have mentioned their association with hepatitis B and their predictive effect after the treatment of hepatitis B with interferon. This article introduces the predictive factors for interferon treatment of CHB and summarizes the association of interferon-stimulated genes with hepatitis B and their predictive effect, so as to provide a reference for clinical work and basic research.
