Analysis of antibiotic use and rationality for children in primary healthcare institutions from Beijing
- VernacularTitle:北京市基层医疗机构儿童抗菌药物使用及合理性分析
- Author:
Taxifulati YUMITI
1
;
Yaoyao YANG
1
;
Shicai CHEN
2
;
Kexin DU
1
;
Yue ZHOU
1
;
Lin HU
1
;
Bo ZHENG
3
;
Xiaodong GUAN
1
;
Wushouer HAISHAERJIANG
1
,
4
;
Luwen SHI
1
Author Information
1. Dept. of Pharmacy Administration and Clinical Pharmacy，School of Pharmaceutical Sciences，Peking University，Beijing 100191，China
2. Dept. of Pharmacy，Beijing Luhe Hospital Affiliated to Capital Medical University，Beijing 101100，China
3. Institute of Clinical Pharmacology，Peking University First Hospital，Beijing 100191，China
4. International Research Center for Medicinal Administration，Peking University，Beijing 100191，China
- Publication Type:Journal Article
- Keywords:
primary healthcare institutions;
children;
antibiotics;
prescription;
rational drug use;
Beijing
- From:
China Pharmacy
2022;33(2):236-243
- CountryChina
- Language:Chinese
-
Abstract:
OBJE CTIVE To inv estigate the antibiotic use and rationality for children in community health service institutions from Beijing ，and to provide reference for promoting rational use of antibiotics in primary healthcare institutions. METHODS All the prescriptions for children from primary healthcare institutions in 2019 were extracted from prescription review system of community health service institutions in Beijing. The use of antibiotics was described according to the related indicators of the World Health Organization/International Network for Rational Use of Drug （WHO/INRUD）. The structure of antibiotics use was analyzed according to the anatomical therapeutic chemical （ATC）classification as well as the WHO AWaRe classification and diagnosis. RESULTS A total of 288 primary healthcare institutions and 10 422 prescriptions for children were included. The number of institutions in high-income areas ，middle-income areas and low-income areas were 119，80 and 89 respectively，and the number of prescriptions involved were 2 430，2 163 and 5 829 respectively，including 1 447 prescriptions involving antibiotics （13.9％）. Among 1 447 prescriptions，the rate of prescriptions involving combined use of antibiotics was 1.4％（20 pieces）；the rate of prescriptions involving antibiotics injection was 9.7％（141 pieces）；4.8％ antibiotics prescriptions were rated as unreasonable （69 pieces）. The three most commonly used antibiotics were the macrolides （40.2％），the second-generation cephalosporins （26.5％） and the third-generati on cephalosporins （23.4％）. The proportion of antibioti cs prescriptions from groups of access ，caution， reserve and not recommended were 9.1％，92.1％，0.3％，and 0， respectively. The rate of antibiotics prescriptions fortonsillitis was the highest （31.9％ ）. Among 69 irrationalantibiotics prescriptions ，main of them were irrational drug use （56 pieces，81.2％）. CONCLUSIONS The rate of antibiotics prescriptions for children in primary healthcare institutions from Beijing is lower than the standard of WHO antibiotics prescription rate （20.0％-26.8％），but the use rate of antibiotics at caution grade is too high.
