Research about clinical comprehensive evaluation methods of pediatric drugs ：taking pediatric anti-allergic drugs as an example
- VernacularTitle:儿童药品临床综合评价方法研究——以儿童抗过敏药物为例
- Author:
Lu LIU
1
;
Yue XIAO
2
;
Chang LIU
1
;
Suxin QU
1
;
Rong LI
1
;
Baodong YU
1
;
Xiaomei MO
1
;
Kejun LIU
2
;
Meixing YAN
1
Author Information
1. Dept. of Pharmacy，Qingdao Women and Children’s Hospital，Shandong Qingdao 266034，China
2. China National Health Development Resear ch Center，Beijing 100044，China
- Publication Type:Journal Article
- Keywords:
pediatric drug;
anti-allergic drug;
clinical comprehensive evaluation
- From:
China Pharmacy
2022;33(2):142-145
- CountryChina
- Language:Chinese
-
Abstract:
OBJEC TIVE To provide reference for clinical comprehensive evaluation of pediatric drugs in China. METHODS Taking pediatric anti-allergic drugs as an example ，the clinical comprehensive evaluation methods of pediatric drugs in medical institutions were explored from the aspects of theme selection ，evaluation content and dimension ，evaluation index ，evaluation method and evaluation result report. RESULTS & CONCLUSIONS During the clinical comprehensive evaluation of pediatric drugs，under the guidance of relevant national guidelines for clinical comprehensive evaluation ，the evaluation topics could be selected according to the three principles of importance ，relevance and evaluability ，and then an appropriate evaluation index system could be developed around the six dimensions of safety ， effectiveness， economy， suitability，accessibility and innovativeness；qualitative and quantitative data integration analysis of the drugs to be evaluated were performed. In the evaluation ， it is necessary to focus on children ’s clinical basic drug use practice and decision-making needs ，normatively，scientifically and reasonably define the core index set and standard data set required by different dimensions of evidence ，standardize the collection and use of real-world data ，and effectively combine other types of evidence to truly play its advantageous role in the clinical comprehensive evaluation of pediatric drugs in China.
