Progress of researches on roles of dendritic cells in immune tolerance caused by Echinococcus infections

VernacularTitle:树突状细胞在棘球蚴感染所致免疫耐受中作用的研究进展
Author: Wen-deng LI ^{1
,

2} ; Wang HU ^{1
,

2} ; Kai XU ^{1
,

2} ; Ru NIE ^{1
,

2} ; Ming-quan PANG ^{1
,

2} ; Hai-ning FAN ^{1
,

2}
Author Information

1. Department of Hepatopancreatobiliary Surgery, the Affiliated Hospital of Qinghai University, Xining, Qinghai 810001, China
2. Qinghai Province Key Laboratory of Hydatid Disease Research, Xining, Qinghai 810001, China
Publication Type:Journal Article
Keywords: Echinococcosis; Dendritic cell; Immune tolerance
From: Chinese Journal of Schistosomiasis Control 2021;33(6):655-659
CountryChina
Language:Chinese
Abstract: Dendritic cells (DCs), a type of antigen-presenting cells (APC), are recognized as an important regulator of immune response and immune tolerance, and play a critical role in the host innate immunity and adaptive immunity. Previous studies have shown that the long-term parasization of Echinococcus in the host is strongly associated with the host immune tolerance induced by DCs. This review summarizes the research progress of the role of DCs in host immune tolerance caused Echinococcus infection, aiming to provide the theoretical basis and insights into the management and immunotherapy of Echinococcus infections.