Evaluation between 3.0 T vs 1.5 T MRI in Detection of Brain Metastasis using Double Dose Gd-DTPA.
- Author:
Woo Suk CHUNG
1
;
Tae Sub CHUNG
;
Hyung Jung KIM
;
Chul Min AHN
;
Jae Hoon LEE
;
Jin HUR
;
Arthur Eung Hyuck CHO
Author Information
1. Department of Diagnostic Radiology and Research Institute of Radiological Science, Yonsei University, College of Medicine, Yong Dong Severance Hospital. tschung@yumc.yonsei.ac.kr
- Publication Type:Original Article
- Keywords:
Magnetic resonance (MR), high-field-strength imaging;
Brain neoplasm, metastases;
Contrast medium
- MeSH:
Brain*;
Gadolinium DTPA*;
Humans;
Lung Neoplasms;
Magnetic Resonance Imaging*;
Neoplasm Metastasis*;
Neoplasm Staging
- From:Journal of the Korean Society of Magnetic Resonance in Medicine
2005;9(2):101-108
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: Early detection of small brain metastases is important. The purpose of this study was to compare the detectability of brain metastases according to the size between 1.5 T and 3.0 T MRI. MATERIALS AND METHODS: We reviewed 162 patients with primary lung cancer who were examined for TNM staging. After administration of double dose of Gd-DTPA, MR imaging was performed with SPGR by 3.0 T MRI and then with T1 SE sequence by 1.5 T MRI. In each patient, three readers performed qualitative assessment. Sensitivity, positive predictive value, and diagnostic accuracy were calculated in 3.0 T and 1.5 T MRI according to size. Using the signal intensity (SI) measurements between the metastatic nodules and adjacent tissue, nodule-to-adjacent tissue SI ratio was calculated. RESULTS: Thirty-one of 162 patients had apparent metastatic nodules in the brain at either 1.5 T or 3.0 T MR imaging. 143 nodules were detected in 3.0 T MRI, whereas 137 nodules were detected at 1.5 T MRI. Six nodules, only detected in 3.0 T MRI, were smaller than 3.0 mm in dimension. Sensitivity, positive predictive value, and diagnostic accuracy in 3.0 T MRI were 100 %, 100 %, and 100 % respectively, and in 1.5 T MRI were 95.8 %, 88.3 %, and 85.1 % respectively. SI ratio was significantly higher in the 3.0 T MRI than 1.5 T MRI (p=0.025). CONCLUSION: True positive rate of 3.0 T MRI with Gd-DTPA was superior to 1.5 T MRI with Gd-DTPA in detection of metastatic nodules smaller than 3.0 mm.
