Value of idiopathic inflammatory myopathy autoantibody profile detection for in clinical application
10.3760/cma.j.cn114452-20210422-00260
- VernacularTitle:特发性炎性肌病自身抗体谱检测在临床应用中的价值
- Author:
Songxin YAN
1
;
Yongzhe LI
Author Information
1. 中国医学科学院 北京协和医学院 北京协和医院检验科 疑难重症及罕见病国家重点实验室，北京 100730
- Keywords:
Myositis;
Autoantibodies
- From:
Chinese Journal of Laboratory Medicine
2021;44(11):995-1002
- CountryChina
- Language:Chinese
-
Abstract:
The Idiopathic inflammatory myopathy (IIM), which collectively referred to as myositis, has been considered as a series of heterogeneous diseases characterized by the proximal symmetrical muscle weakness and involvement of multiple organs (such as skin, joints, lungs, gastrointestinal tract, and heart). IIM mainly includes the polymyositis, dermatomyositis, inclusion body myositis and other clinical subtypes. Although the pathogenesis of IIM is not clear, but myositis autoantibodies have been considered to play a certain role in the development and diagnosis of the disease. Myositis autoantibodies can be divided into myositis-specific autoantibodies or myositis-associated autoantibodies. This review provides a comprehensive summary of the progress in the related field of myositis autoantibodies in recent years, hoping to further demonstrate the clinical value of myositis autoantibodies and promote the clinical application of myositis autoantibodies.
