Advances in microdialysis-coupled microfluidics for body fluid monitoring
10.3760/cma.j.cn114452-20210726-00456
- VernacularTitle:微透析与微流控技术联合应用于体液监测的研究进展
- Author:
Xingbei ZHOU
1
;
Tao DING
;
Shushui WANG
Author Information
1. 华南理工大学医学院，广州 510006
- Keywords:
Microdialysis;
Microfluidic;
Biochemical monitoring;
Liquid biopsy;
Blood detection;
Neurotransmitters
- From:
Chinese Journal of Laboratory Medicine
2021;44(10):970-977
- CountryChina
- Language:Chinese
-
Abstract:
Microdialysis is a novel technique for rapid and continuous sampling of body fluid in the extracellular space, especially for some hard-to-obtain samples, e.g. cerebrospinal fluid, interstitial fluid. Microfluidic technology plays a significant role in body fluid analysis because of its miniaturization, high-throughput, and automation, offering a feasible method for rapid and low-cost biochemical analysis. In clinical practice, body fluid analysis is often required to be fast and/or capable of long-termly monitoring certain biomarkers. However, current technologies are insufficient to meet this requirement. The combination of microdialysis and microfluidic technologies could provide a new perspective to solve this problem.
