Research advances on circulating exosomal microRNAs as novel biomarkers of atherosclerotic cardiovascular diseases

VernacularTitle:循环外泌体微小RNA：动脉粥样硬化性心血管疾病新型标志物
Author: Jia WU ¹ ; Junjun WANG
Author Information

1. 解放军东部战区总医院检验科，南京　210002
Keywords: Exosomes; microRNA; Atherosclerosis; Biological markers
From: Chinese Journal of Laboratory Medicine 2021;44(7):558-562
CountryChina
Language:Chinese
Abstract: Exosomal microRNAs (miRNAs) from various cell sources in the cardiovascular system are involved in the regulation of diverse biological processes such as angiogenesis, myocardial remodeling, inflammation and plaque rupture, and may function as promising liquid biomarkers for atherosclerotic cardiovascular diseases (ASCVD). Expression analysis of exosomal miRNAs can be employed for monitoring ASCVD progression and evaluating treatment efficiency. This review focused on recent research advances regarding exosomal miRNAs in the field of ASCVD laboratory medicine, and summarized the future research trends and application prospects of circulating exosomal miRNAs in the field of ASCVD.