Potential value of extracellular vesicles/exosomes in diagnosis and treatment of COVID-19
10.3760/cma.j.cn114452-20201015-00775
- VernacularTitle:细胞外囊泡/外泌体在新型冠状病毒肺炎诊治中的潜在价值
- Author:
Bokun ZHENG
1
;
Yueting TANG
;
Yirong LI
Author Information
1. 武汉大学中南医院检验科，武汉430071
- Keywords:
Extracellular vesicles;
Exosomes;
COVID-19;
2019-nCoV
- From:
Chinese Journal of Laboratory Medicine
2021;44(6):537-541
- CountryChina
- Language:Chinese
-
Abstract:
Since the outbreak of the novel coronavirus pneumonia (COVID-19), it is urgently to develop the effective strategies for its clinical test or treatments world widely. Extracellular vesicles (EV)/exosomes could function as effective carriers for intercellular communication. Increasing evidence revealed that mesenchymal stem cell-derived EV/exosomes could be considered as an alternative cell-free therapy against the acute respiratory distress syndrome. Moreover, the EV-related metabolomics, proteomics, relapsing, deep-vein-thrombosis, myocardial-toxicity, liquid-biopsy and bio-therapeutic researches focusing on the COVID-19 will not only extended our knowledge for the diagnosis, but also provide novel ideas for treatment of this fatal disease. This article will systemically review the progresses of EV/exosomes in the diagnosis and treatment of COVID-19.
