Analysis of peripheral pathological features of diabetic retinopathy based on ultra-wide-angle fundus imaging
10.3760/cma.j.cn511434-20200928-00475
- VernacularTitle:基于超广角眼底成像的糖尿病视网膜病变周边病变特征分析
- Author:
Xuenan ZHUANG
1
;
Dan CAO
;
Jie YAO
;
Ruoyu CHEN
;
Yesheng CHEN
;
Zicheng WANG
;
Liang ZHANG
Author Information
1. 广东省人民医院眼科 广东省眼病防治研究所 广东省医学科学院，广州 515000
- Keywords:
Diabetic retinopathy;
Predominantly peripheral lesions;
Ultra-wide field imaging
- From:
Chinese Journal of Ocular Fundus Diseases
2021;37(7):523-527
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the distribution characteristics of peripheral retinopathy in Chinese patients with diabetic retinopathy (DR).Methods:A cross-sectional study. From January to December 2019, 265 cases of 388 eyes of DR patients diagnosed in the eye examination of Guangdong Provincial People's Hospital were included in the study. Among them, there were 211 eyes in 148 males and 177 eyes in 117 females; the average age was 58.4±12.3 years. Ultra-wide-angle fundus imaging (UWF) examination was performed by Daytona in Aalborg, UK. Use Photoshop to simulate the standard 7-azimuth (S7F) area, which was used as the central retinal area 1-7. The peripheral retinal areas 3-7 (P3-P7) were the adjacent peripheral retinal areas of the central retinal area 3-7, respectively. Divided DR into peripheral lesion predominant type (PPL) and central lesion predominant type (PCL). PPL was defined as at least one peripheral retinal area with more severe disease than its adjacent central area. χ 2 test was performed on the difference of PPL composition ratio in each retinal area of eyes with different DR stages. Results:Among 388 eyes, 200 eyes were PPL (51.5%, 200/388). Compared of PPL composition ratios of eyes with different stages of DR, mild non-proliferative DR (NPDR), moderate NPDR, severe NPDR and proliferative DR were 32 (36.8%, 32/87), 89 (55.3%, 89/161)), 42 (51.9%, 42/81), 37 (62.6%, 37/59), the difference was statistically significant ( χ2=11.440, P=0.010). Comparison of the distribution of PPL in each retinal area in DR eyes: in 200 PPL eyes, areas 3, 4, 5, 6, and 7 have 87, 101, 78, 67, and 38 eyes, respectively. The distribution of PPL in each retinal area in DR eyes was compared, and the difference was statistically significant ( χ2=37.640, P<0.001). Conclusions:PPL accounts for 51.5% of the eyes with DR. The DR stage are more severe, the proportion of PPL is higher. The temporal retinal peripheral lesions are the most common.
