Preschool period neurodevelopmental follow-up in children underwent antergrade cerebral perfusion
10.3760/cma.j.cn112434-20201020-00474
- VernacularTitle:顺行区域性脑灌注术后学龄前期神经发育随访研究
- Author:
Jinjin HUANG
1
;
Huiying JIN
;
Yong FAN
;
Haifeng LI
;
Ru LIN
;
Lifen YE
Author Information
1. 杭州国家儿童健康与疾病临床医学研究中心 浙江大学医学院附属儿童医院心脏中心 310052
- Keywords:
Antergrade cerebral perfusion;
Preschool period;
Griffiths mental development scale
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2021;37(9):557-560
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the preschool period neurodevelopmental status and analyze the perioperative data which associated with delayed neurodevelopment in patients underwent antergrade cerebral perfusion(ACP).Methods:To access the preschool period neurodevelopmental status in patients underwent ACP using Griffiths mental development scale-Chinese(GDS-C). Patients were classified as normal development group(ND) and low development group(LD) depending on the outcomes of assessment. Perioperative data including age, weight, CPB time, aortic cross-clamp time, mean arterial pressure, ACP time and flow were analyzed retrospectively.Results:62 children who met the inclusion criteria, of which 19 were accessed by GDS-C scale. Fourteen cases were lagged in general quotient(GQ) compared with normal children. The outcomes of assessment in six subscales of GDS-C scale indicated that 13 cases were delayed in language(C) and practical reasoning(F). Eight cases were delayed in locomotor(A) and personal-social(B). Eleven cases were delayed in eye-hand coordination(D). Ten cases were delayed in performance(E). The children in LD group had significant longer CPB time and aortic cross-clamp time than those in ND group. There were no differences between two groups in other perioperative data.Conclusion:The incidence of preschool period neurodevelopmental delay after ACP in infants is relatively high. In detailed analysis, their language and practical reasoning ability are lagged significantly. In addition, the longer time of CPB and aortic cross-clamp are associated with the neurodevelopmental delay.
