Etiology and current treatment status of 277 patients with chronic atrophic gastritis and erosion in Beijing area
10.3760/cma.j.cn311367-20210718-00390
- VernacularTitle:北京地区慢性萎缩性胃炎伴糜烂患者277例的病因和治疗现状
- Author:
Yingyun YANG
1
;
Yuan LI
;
Haifang ZHANG
;
Xiaoyun CHENG
;
Yuxia GUAN
;
Jing WANG
;
Shujuan JIA
;
Shigang DING
;
Jingnan LI
Author Information
1. 中国医学科学院 北京协和医学院 北京协和医院消化内科 中国医学科学院肠道微生态临床疾病转化研究重点实验室 100730
- Keywords:
Chronic erosive gastritis;
Lifestyle factors;
Symptoms;
Endoscopic findings;
Treatment
- From:
Chinese Journal of Digestion
2021;41(Z1):27-32
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To preliminarily understand the living habits, medication taking and treatment status including the therapeutic regimen, compliance and short-term efficacy of patients with chronic atrophic gastritis and erosion in Beijing area.Methods:From April to September in 2019 at Peking Union Medical College Hospital, Peking University Third Hospital and Peking University Shougang Hospital, the outpatients with chronic atrophic gastritis and erosion diagnosed with endoscopy within two weeks before visiting were prospectively included in this non-interventional observation study. Chi square test was used for statistical analysis.Results:A total of 277 patients with chronic atrophic gastritis and erosion had complete follow-up data, of which male patients accounted for 49.8% (138/277). The common initial symptoms of patients with chronic atrophic gastritis and erosion included acid reflux, abdominal distension, epigastric pain and postprandial distension, which accounted for 60.3% (167/277), 59.6% (165/277) , 58.8% (163/277) and 52.3% (145/277), respectively. For treatment, 36.8% (102/277) of the patients only received lifestyle instruction without medication. Among the patients with medication treatment, the short-term efficacy of gastric mucosal protectants+ proton pump inhibitor+ gastro-kinetic agent for abnominal distension, postprandial distention, acid reflux and nausea was highest as compared with other therapeutic regimen, and the differences were statistically significant ( χ2=25.18, 19.49, 13.75, 8.84, all P<0.05). Conclusions:Chronic gastritis with erosion may be caused by a combination of multiple factors, and the symptoms of which lack specific. If necessary, gastroscopy may help the diagnosis. Individualized treatment strategies based on the symptoms of patients is needed for treatment.
