Preliminary clinical observation on endoscopic longitudinal incision combined with bleomycin local injection for complex benign esophageal strictures
10.3760/cma.j.cn321463-20200927-00660
- VernacularTitle:内镜下纵行切开联合博来霉素局部注射治疗复杂性食管良性狭窄的初步临床观察
- Author:
Tongzhen ZHANG
1
;
Shoubin NING
;
Tao SUN
;
Nianjun XIAO
;
Xin YIN
;
Rui GUO
;
Jing ZHANG
Author Information
1. 空军特色医学中心消化内科，北京 100142
- Keywords:
Esophageal stenosis;
Complex benign esophageal strictures;
Longitudinal incision;
Bleomycin local injection
- From:
Chinese Journal of Digestive Endoscopy
2021;38(11):916-920
- CountryChina
- Language:Chinese
-
Abstract:
Data of 7 patients with complex benign esophageal strictures (CBESs) who underwent endoscopic longitudinal incision combined with local injection of bleomycin were retrospectively reviewed at Air Force Medical Center from August 2018 to November 2019.The length of preoperative esophageal stenosis was 4-14 cm and the minimum diameter of esophageal stenosis was 0.2-0.4 cm in 7 cases. The procedure was successful for all 7 patients.No adverse events occurred during 5-14 months of follow-up period.Restenosis and dysphagia occurred in 5 cases.The interval between the first endoscopic treatment and the recurrence of esophageal stenosis was 30-120 days.Among the 5 cases of recurrence, 4 cases remained unobstructed after 2 treatments and 1 case remained unobstructed after 4 treatments. The dysphagia scores of 7 patients were graded from 0 to 1 by the end of follow-up. Endoscopic longitudinal incision combined with bleomycin therapy in treatment of CBESs is safe and effective.
