Application of pushing endoscopic submucosal dissection in large area of early cancer and precancerous lesions of cardia
10.3760/cma.j.cn321463-20200417-00086
- VernacularTitle:注水黏膜切开刀推进式内镜黏膜下剥离术快速切除贲门大面积早期癌及其癌前病变的应用初探
- Author:
Ying XIONG
1
;
Jing HAN
;
Yanan ZHU
;
Yujie CHEN
;
Congran HOU
;
Zhanjiang YU
;
Xuemei GAO
;
Jinzhuo ZHANG
Author Information
1. 保定市第一中心医院消化三科 071000
- Keywords:
Cardia;
Endoscopic submucosal dissection;
Water-injected knife;
Early carcinoma;
Precancerous lesion
- From:
Chinese Journal of Digestive Endoscopy
2021;38(6):479-483
- CountryChina
- Language:Chinese
-
Abstract:
To explore the application value of pushing endoscopic submucosal dissection (PESD) in treatment of large area of early cardiac cancer or precancerous lesions. Form January 2017 to January 2020, patients diagnosed as having early cardiac cancer or high-grade intraepithelial neoplasia with largest lesion diameter greater than 2.0 cm at the Baoding NO.1 Central Hospital were enrolled in the study. Patients who received PESD with water-injected knife were included in the PESD group (26 cases), and compared with those who received conventional ESD with common mucosal incision (the conventional ESD group, 17 cases) at the same period. The procedure time, the complete resection rate of lesions and the incidence of complications were analyzed.There were no difference in lesion size between the two groups ( P>0.05). The procedure time of PESD group was 53.7±18.2 min, which was 91.5±26.5 min in the conventional ESD group, and the difference was statistically significant ( P<0.001). In the PESD group, 7 cases (26.9%) had intraoperative hemorrhage. In the conventional ESD group, 8 cases (47.1%) had intraoperative bleeding, and 2 (11.8%) had intraoperative perforation. There were significant differences in the incidence of hemorrhage and perforation between the two groups (all P<0.001). Compared with conventional ESD, PESD can effectively improve the dissection speed, reduce the incidence of complications, and make endoscopic surgery safer and faster.
