Research progress on the anti-inflammatory effect of interleukin 37 and its role in asthma
10.3760/cma.j.cn112309-20201110-00509
- VernacularTitle:IL-37的抗炎作用机制及其在哮喘中的研究进展
- Author:
Shengnan GAO
1
;
Jiangtao LIN
Author Information
1. 北京协和医学院研究生院，中国医学科学院 100730
- Keywords:
IL-37;
Asthma;
Inflammatory;
Immunity;
Cytokine
- From:
Chinese Journal of Microbiology and Immunology
2021;41(6):488-492
- CountryChina
- Language:Chinese
-
Abstract:
IL-37 is a member of the IL-1 family of cytokines, which functions as a natural suppressor of inflammatory and immune responses. IL-37 likely functions to limit excessive inflammation, accordingly, IL-37 levels are abnormal in patients with inflammatory and autoimmune diseases. In this review, we provide an overview of the anti-inflammatory mechanism of IL-37. It also summarizes the research progress of expression and its role in bronchial asthma, a heterogeneous chronic airway inflammatory disease.
